An AI platform that integrates clinical context, payer guidelines, and operational execution for oncology treatment access and reimbursement workflows.

Part B Auths.
Part D Auths.
One Platform.
OneRISA

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Workflow

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Delivering speed, accuracy, and efficiency across every step.

STEP 01 / ELIGIBILITY

Eligibility & Benefits Verification

Instant access to patient copay, deductibles, and out-of-pocket costs. Calculates Patient Financial Responsibility to provide an accurate cost estimate.

INSURANCE A · PRIMARY

Active

Co-Pay

$40

Co-Insurance

20%

Deductible Remaining

$188

Patient Responsibility

$228

STEP 02 / VERIFICATION

Authorization Verification

Checks if authorization is needed through payer guidelines. In cases of authorization on file, reads prior approvals and denial letters, and evaluates visit counts for accurate next-DOS evaluation.

PAYER RULE CHECK

UHC · ONC POLICY v2024.3

Authorization required

J9263 · Oxaliplatin

Auth on file

· 3 visits remaining

No prior denial

clear to submit

STEP 03 / MEDICAL NECESSITY

Medical Necessity Assessment & Recommendation

Leverages evidence-based and payer guidelines to create automated checklists, assessing each item to provide clear approval or denial recommendations.

REGIMEN: FOLFOX · ICD-10 C50.912

CRITERIA 4/5

One of the following criteria should be met:

Combination therapy with fluorouracil-based chemotherapy regimens;OR

J0640: Injection, leucovorin calcium, 50mg

J8540: Fluorouracil, oral, 500mg

J9263: Injection, oxaliplatin, 0.5mg

STEP 04 / SUBMISSION

Prior Authorization Submission

Auto-populates and submits PA forms with all required clinical documents and questionnaires.

PACKET — PATIENT 4821 · FOLFOX

PA Form

· UHC standard

FILED

Clinical Notes

· 4 attached

FILED

ICD-10 + HCPCS

· C50.912 / J0640+

FILED

Questionnaire

· auto-populated

FILED

STEP 05 / TRACKING

Real-Time Status Tracking

Constant updates and real-time status tracking from payer portals, e-fax, and email — no portal logins required from your team.

CASE 4821 · ACTIVITY

UPDATED 2m AGO

Apr 22 · 09:14

Received by UHC

Apr 22 · 09:16

Under clinical review

now · ETA 2-3 Days

Determination

pending

STEP 06 / APPEALS · NEW

Automated Appeal Letters

Best-in-class appeal letters crafted by analyzing research and medical necessity guidelines — drawing directly on the payer's own policy language.

APPROVED APPEAL LETTER

(ICD-10: C34.90, Malignant Neoplasm of the Lung)

The patient's diagnosis  is a covered condition per the Oncology Benefits policy. The requested regimen aligns with NCCN guidelines for the stated line of therapy and satisfies medical necessity criteria on file.

— OneRISA, Medical Necessity Appeals Engine

STEP 01 / ELIGIBILITY

Eligibility & Benefits Verification

Instant access to patient copay, deductibles, and out-of-pocket costs. Calculates Patient Financial Responsibility to provide an accurate cost estimate.

INSURANCE A · PRIMARY

Active

Co-Pay

$40

Co-Insurance

20%

Deductible Remaining

$188

Patient Responsibility

$228

STEP 02 / VERIFICATION

Authorization Verification

Checks if authorization is needed through payer guidelines. In cases of authorization on file, reads prior approvals and denial letters, and evaluates visit counts for accurate next-DOS evaluation.

PAYER RULE CHECK

UHC · ONC POLICY v2024.3

Authorization required

J9263 · Oxaliplatin

Auth on file

· 3 visits remaining

No prior denial

clear to submit

STEP 03 / MEDICAL NECESSITY

Medical Necessity Assessment & Recommendation

Leverages evidence-based and payer guidelines to create automated checklists, assessing each item to provide clear approval or denial recommendations.

REGIMEN: FOLFOX · ICD-10 C50.912

CRITERIA 4/5

One of the following criteria should be met:

Combination therapy with fluorouracil-based chemotherapy regimens;OR

J0640: Injection, leucovorin calcium, 50mg

J8540: Fluorouracil, oral, 500mg

J9263: Injection, oxaliplatin, 0.5mg

STEP 04 / SUBMISSION

Prior Authorization Submission

Auto-populates and submits PA forms with all required clinical documents and questionnaires.

PACKET — PATIENT 4821 · FOLFOX

PA Form

· UHC standard

FILED

Clinical Notes

· 4 attached

FILED

ICD-10 + HCPCS

· C50.912 / J0640+

FILED

Questionnaire

· auto-populated

FILED

STEP 05 / TRACKING

Real-Time Status Tracking

Constant updates and real-time status tracking from payer portals, e-fax, and email — no portal logins required from your team.

CASE 4821 · ACTIVITY

UPDATED 2m AGO

Apr 22 · 09:14

Received by UHC

Apr 22 · 09:16

Under clinical review

now · ETA 2-3 Days

Determination

pending

STEP 06 / APPEALS · NEW

Automated Appeal Letters

Best-in-class appeal letters crafted by analyzing research and medical necessity guidelines — drawing directly on the payer's own policy language.

APPROVED APPEAL LETTER

(ICD-10: C34.90, Malignant Neoplasm of the Lung)

The patient's diagnosis  is a covered condition per the Oncology Benefits policy. The requested regimen aligns with NCCN guidelines for the stated line of therapy and satisfies medical necessity criteria on file.

— OneRISA, Medical Necessity Appeals Engine

Results
Outcomes from live oncology practices.
Measured, not projected. Each number is reconciled against source EMR and payer data from practices running OneRISA today.
97%
First submission success rate
APPROVED THE FIRST TIME
<2hr
Prior Auth filingturnaround time
ACCELERATED SUBMISSIONS
5/10
Treatment delays preventedby medical necessity AI
DENIALS PREDICTED. DELAYS PREVENTED
70%
FTE time reclaimed; hours returned to patient-facing work
INCREASED EFFICIENCY
30%
Touchless authorizations and growing: fully automated, end-to-end
INCREASED EFFICIENCY
21days
Ahead of DOS; All auths are filed 3 weeks before the Date of Service
NO LAST-MIN SCRAMBLE
0day
0 Day backlog achieved; compared to delays of up to 8 days previously
NO BACKLOGS
10%
Higher approval through client approved biosimilar filing
Proactive Denial MGMT
Client stories
What RISA is building is not just smart technology. It removes barriers so ourteams can move faster and stay focusedon what matters most: caring for patients.
Dr. Jeff Vacirca, MD, FACP
Chief Executive Officer
Full visibility into every authorization!
We are extremely happy with what RISA is doing. My team now has complete insight into volumes, denials, turnaround times, and clinical alignment.
Dr. Edward Licitra, MD
Chief Executive Officer
RISA is the safety net.
In oncology, drug risk is existential. A tool like RISA acts as a safety net, automating the authorization workflow end-to-end so we shorten time to treatment, reduce errors, and take pressure off staffing.
Nirav Shah
Chief Revenue Officer
After 20+ years in authorizations, RISA is one of the most helpful systems I've used. It simplifies workflows, improves visibility, and makes managing cases far easier. When I’ve shown it to other team members, their reaction has been, ‘Where has this been all my life?’, that really reflects the value it brings.
Maria Langhorst
Senior Manager, RCM
Coverage
800+ medications covered across specialties.
Oncology-first, built to serve the adjacent specialties and ancillary services an oncology practice actually runs.
oncology
Urology
hematology
Cardio-Oncology
endocrinology
Gastroenterology
Pulmonology
Dermatology
Neurology
Infectious Disease
Psychiatry / Behavioral Health
Pain & Palliative Care
Nephrology
Rheumatology
Top Covered Payers
TOP COVERED PBMs
Key Functional Features
Every detail, designed for oncology. Built from the ground up for the clinical and operational complexity that generic tools simply can't handle.
01
Flags for New Line of Therapy vs. Continuation of Therapy
02
Biosimilar Recommendation
03
Guidelines Attached for Human Review
04
Automated Updates in the EMR
05
Complete Traceability at Each AI Decision Point
06
Human-in-the-Loop Workflow
Discover
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Partner Institutions
Outcomes from live oncology practices. Measured, not projected. Each number is reconciled against source
EMR and payer data from practices running OneRISA today.
97%
First submission
success rate
INDUSTRY AVG ~65%
5/10
Denials saved through medical necessity AI, backed by our research paper
23 CITATIONS
70%
FTE time reclaimed — hours returned to patient-facing work
23 CITATIONS
30%
Touchless authorizations — fully automated, end-to-end
23 CITATIONS
Workflow

Delivering speed, accuracy, and efficiency across every step.

STEP 01 / ELIGIBILITY

Eligibility & Benefits Verification

Instant access to patient copay, deductibles, and out-of-pocket costs. Calculates Patient Financial Responsibility to provide an accurate cost estimate.

INSURANCE A · PRIMARY

LIVE

Co-Pay

$40

Co-Insurance

20%

Deductible Remaining

$188

Patient Responsibility

$228

STEP 01 / ELIGIBILITY

Eligibility & Benefits Verification

Instant access to patient copay, deductibles, and out-of-pocket costs. Calculates Patient Financial Responsibility to provide an accurate cost estimate.

PAYER RULE CHECK

UHC · ONC POLICY v2024.3

Authorization required

for J9263 · Oxaliplatin

Auth on file

· 3 visits remaining

No prior denial

on record · clear to submit

arrow right

STEP 01 / ELIGIBILITY

Eligibility & Benefits Verification

Instant access to patient copay, deductibles, and out-of-pocket costs. Calculates Patient Financial Responsibility to provide an accurate cost estimate.

INSURANCE A · PRIMARY

LIVE

Co-Pay

$40

Co-Insurance

20%

Deductible Remaining

$188

Patient Responsibility

$228

STEP 02 / VERIFICATION

Authorization Verification

Checks if authorization is needed through payer guidelines. In cases of authorization on file, reads prior approvals and denial letters, and evaluates visit counts for accurate next-DOS evaluation.

PAYER RULE CHECK

UHC · ONC POLICY v2024.3

Authorization required

for J9263 · Oxaliplatin

Auth on file

· 3 visits remaining

No prior denial

on record · clear to submit

STEP 03 / MEDICAL NECESSITY

Medical Necessity Assessment & Recommendation

Leverages evidence-based and payer guidelines to create automated checklists, assessing each item to provide clear approval or denial recommendations.

REGIMEN: FOLFOX · ICD-10 C50.912

CRITERIA 4/5

One of the following criteria should be met:

Combination therapy with fluorouracil-based chemotherapy regimens; OR

J0640: Injection, leucovorin calcium, 50mg

J9263: Injection, oxaliplatin, 0.5mg

STEP 04 / SUBMISSION

Prior Authorization Submission

Auto-populates and submits PA forms with all required clinical documents and questionnaires.

PACKET — PATIENT 4821 · FOLFOX

21d AHEAD OF DOS

PA Form

· UHC standard

FILED

Clinical Notes

· 4 attached

FILED

ICD-10 + HCPCS

· C50.912 / J0640+

FILED

Questionnaire

· auto-populated

FILED

STEP 05 / TRACKING

Real-Time Status Tracking

Constant updates and real-time status tracking from payer portals, e-fax, and email — no portal logins required from your team.

CASE 4821 · ACTIVITY

UPDATED 2m AGO

Apr 22 · 09:14

Received by UHC

Apr 22 · 09:16

Under clinical review

now · ETA 24h

Determination

pending

STEP 06 / APPEALS · NEW

Automated Appeal Letters

Best-in-class appeal letters crafted by analyzing research and medical necessity guidelines — drawing directly on the payer's own policy language.

APPROVED APPEAL LETTER

23 CITATIONS

The patient's diagnosis

(ICD-10: C34.90, Malignant Neoplasm of the Lung)

is a covered condition per the Oncology Benefits policy. The requested regimen aligns with NCCN guidelines for the stated line of therapy and satisfies medical necessity criteria on file.

— OneRISA, Medical Necessity Appeals Engine

Workflow

Delivering speed, accuracy, and efficiency across every step.

STEP 01 / ELIGIBILITY

Eligibility & Benefits Verification

Instant access to patient copay, deductibles, and out-of-pocket costs. Calculates Patient Financial Responsibility to provide an accurate cost estimate.

INSURANCE A · PRIMARY

LIVE

Co-Pay

$40

Co-Insurance

20%

Deductible Remaining

$188

Patient Responsibility

$228

STEP 02 / VERIFICATION

Authorization Verification

Checks if authorization is needed through payer guidelines. In cases of authorization on file, reads prior approvals and denial letters, and evaluates visit counts for accurate next-DOS evaluation.

PAYER RULE CHECK

UHC · ONC POLICY v2024.3

Authorization required

for J9263 · Oxaliplatin

Auth on file

· 3 visits remaining

No prior denial

on record · clear to submit

STEP 03 / MEDICAL NECESSITY

Medical Necessity Assessment & Recommendation

Leverages evidence-based and payer guidelines to create automated checklists, assessing each item to provide clear approval or denial recommendations.

REGIMEN: FOLFOX · ICD-10 C50.912

CRITERIA 4/5

One of the following criteria should be met:

Combination therapy with fluorouracil-based chemotherapy regimens; OR

J0640: Injection, leucovorin calcium, 50mg

J9263: Injection, oxaliplatin, 0.5mg

STEP 04 / SUBMISSION

Prior Authorization Submission

Auto-populates and submits PA forms with all required clinical documents and questionnaires.

PACKET — PATIENT 4821 · FOLFOX

21d AHEAD OF DOS

PA Form

· UHC standard

FILED

Clinical Notes

· 4 attached

FILED

ICD-10 + HCPCS

· C50.912 / J0640+

FILED

Questionnaire

· auto-populated

FILED

STEP 05 / TRACKING

Real-Time Status Tracking

Constant updates and real-time status tracking from payer portals, e-fax, and email — no portal logins required from your team.

CASE 4821 · ACTIVITY

UPDATED 2m AGO

Apr 22 · 09:14

Received by UHC

Apr 22 · 09:16

Under clinical review

now · ETA 24h

Determination

pending

STEP 06 / APPEALS · NEW

Automated Appeal Letters

Best-in-class appeal letters crafted by analyzing research and medical necessity guidelines — drawing directly on the payer's own policy language.

APPROVED APPEAL LETTER

23 CITATIONS

The patient's diagnosis

(ICD-10: C34.90, Malignant Neoplasm of the Lung)

is a covered condition per the Oncology Benefits policy. The requested regimen aligns with NCCN guidelines for the stated line of therapy and satisfies medical necessity criteria on file.

— OneRISA, Medical Necessity Appeals Engine